Original Research Articles since 2000

Roos R, Andersson PL, Halldin K, Hǻkansson H, Westerholm E, Hamers T, Hamscher G, Heikkinen P, Korkalainen M, Leslie HA, Niittynen M, Sankari S, Schmitz HJ, van der Ven LT, Viluksela M, Schrenk D:
Hepatic effects of a highly purified 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in male and female rats. Toxicology, epub (2011).

Guth S, Habermeyer M, Schrenk D, Eisenbrand G:
Update of the toxicological assessment of furanocoumarins in foodstuffs (Update of the SKLM statement of 23/24 September 2004) - Opinion of the Senate Commission on Food Safety (SKLM) of the German Research Foundation (DFG). Mol. Nutr. Food Res., epub (2011).

Chopra M, Schrenk D:
Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis-Persistent pollutants affect programmed cell death. Crit. Rev. Toxicol. 41, 292-320 (2011).

Soyalan B, Minn J, Schmitz HJ, Schrenk D, Will F, Dietrich H, Baum M, Eisenbrand G, Janzowski C:
Apple juice intervention modulates expression of ARE-dependent genes in rat colon and liver. Eur. J. Nutr. 50, 135-143 (2011).

Kahle K, Kempf M, Schreier P, Scheppach W, Schrenk D, Kautenburger T, Hecker D, Huemmer W, Ackermann M, Richling E.:
Intestinal transit and systemic metabolism of apple polyphenols. Eur. J. Nutr., epub (2010).

Fery Y, Mueller SO, Schrenk D:
Development of stably transfected human and rat hepatoma cell lines for the species-specific assessment of xenobiotic response enhancer module (XREM)-dependent induction of drug metabolism. Toxicology 277, 11-19 (2010).

Mally A, Graff C, Schmal O, Moro S, Hamberger C, Schauer UM, Brück J, Ozden S, Sieber M, Steger U, Schrenk D, Hard GC, Chipman JK, Dekant W.:
Functional and proliferative effects of repeated low-dose oral administration of furan in rat liver. Mol. Nutr. Food Res. 54, 1556-1567 (2010).

Chopra M, Gährs M, Haben M, Michels C,
Schrenk D:
Inhibition of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin depends on protein biosynthesis. Cell Biol. Toxicol. 26, 391-401 (2010).

Bach A, Bender-Sigel J, Schrenk D, Flügel D, Kietzmann T:
The antioxidant quercetin inhibits cellular proliferation via HIF-1-dependent induction of p21WAF. Antiox. Redox Signal. 13, 437-448 (2010).

Müller SO, Fery Y, Tuschl G, Schrenk D:
Species-specific activation of nuclear receptors correlates with the response of liver drug metabolizing enzymes to EMD 392949 in vitro. Toxicol. Lett. 193, 120-123 (2010).

Lohr C, Raquet N, Schrenk D:
Relative phototoxic and photomutagenic potencies of selected furocoumarins in V79 cells. Toxicol. In Vitro 24, 558-566 (2010).

Gorgus E, Lohr C, Guth S, Raquet N, Schrenk D:
Limettin and furocoumarins in beverages containing citrus juices or extracts. Food Chem. Toxicol. 48, 93-98 (2010).

Chopra M, Link P, Michels C, Schrenk D:
Characterization of Ochratoxin A-induced apoptosis in primary rat hepatocytes. Cell Biol. Toxicol., epub. (2009).

Chopra M, Dharmarajan AM, Meiss G, Schrenk D:
Inhibitiion of UV-C light-induced apoptosis in liver cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol. Sci. 111, 49-63 (2009).

Schrenk D:
Dietary fiber, low-molecular-weight food constituents and colo-rectal inflammation in animal models - a review. Mol. Nutr. Food Res. 53, 1281-1288 (2009).

Schrenk D:
The interaction of food and intestinal health has gained considerable interest in the recent years. Mol. Nutr. Food Res. 53, 1209 (2009).

Biesalski HK, Dragsetd LO, Elmadfa I, Grossklaus R, Müller M, Schrenk D, Walter P, Weber P:
Bioactive compounds: definition and assessment of activity. Nutrition 25, 1202-1205 (2009).

Biesalski HK, Dragsetd LO, Elmadfa I, Grossklaus R, Müller M, Schrenk D, Walter P, Weber P:
Bioactive compounds: safety and efficacy. Nutrition 25, 1206-1211 (2009).

Fery Y, Buschauer I, Salzig C, Lang P, Schrenk D:
Inhibitiion of UV-C light-induced apoptosis in liver cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicology 264, 45-51 (2009).

Raquet N, Schrenk D:
Relative photomutagenicity of furocoumarins and limettin in the HPRT assay in V79 cells. Chem. Res. Toxicol. 22, 1639-1647 (2009).

Glaube F, Wölfl S, Pusch L, Werner U, Kroll TC, Schrenk D, Hartmann RW, Hamburger M:
Effects of Leuzea carthamoides on human breast adenocarcinoma MCF-7 cells determined by gene expression profiling and functional assays. Planta Medica 74, 1701-1708 (2008)

van der Ven LTM, van de Kuil T, LeonardsPEG, Slob W, Cantón RF, Germer S, Visser TJ, Litens S, Håkansson H, Schrenk D, van den BergM, PiersmaAH, Vos JG:
A 28-day oral dose toxicity study in Wistar rats enhanced to detect endocrine effects of decabromodiphenyl ether (decaBDE). Toxicol. Lett. 179, 6-14 (2008)

van der Ven LTM, van de Kuil T, LeonardsPEG, Slob W, Cantón RF, Germer S, Visser TJ, Litens S, Håkansson H, Schrenk D, van den BergM, PiersmaAH and Vos JG:
A 28-day oral dose toxicity study in Wistar rats enhanced to detect endocrine effects of decabromodiphenyl ether (decaBDE). Toxicololy 245, 109-122 (2008)

Waldecker M, Kautenburger T, Daumann H, Veeriah S, Will F, Dietrich H, Pool-Zobel BL and Schrenk D:
Histone-deacetylase inhibition and butyrate formation: Fecal slurry incubations with apple pectin and apple juice extracts. Nutrition 24, 366-374 (2008).

Waldecker M, Kautenburger T, Daumann H, Busch C and Schrenk D:
Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon. J. Nutr. Biochem. E-Publication (2007).

Berggren S, Gall C, Wollnitz N, Ekelund M, Karlbom U, Hoogstraate J, Schrenk D and Lennernäs H:
Gene and protein expression of P-glycoprotein, MRP1, MRP2, and CYP3A4 in the small and large human intestine. Mol. Pharm. 4, 252-257 (2007)

Pohl C, Will F, Dietrich H and Schrenk D:
Cytochrome P450 1A1 expression and activity in Caco-2 cells: modulation by apple juice extract and certain apple polyphenols. J. Agric. Food Chem. 54, 10262-10268 (2006).

Knerr S and Schrenk D:
Carcinogenicity of "non-dioxinlike" polychlorinated biphenyls. Crit. Rev. Toxicol. 36, 663-694 (2006).

Knerr S and Schrenk D:
Carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in experimental models. Mol. Nutr. Food Res. 50, 897-907 (2006).

Van den Berg M, Birnbaum LS, Denison M, De Vito M, Farland W, Feeley M, Fiedler H, Hakansson H, Hanberg A, Haws L, Rose M, Safe S, Schrenk D, Tohyama C, Tritscher A, Tuomisto J, Tysklind M, Walker N and Peterson RE:
The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol. Sci. 93, 223-241 (2006).

Knerr S, Schaefer J, Both S, Mally A, Dekant W and Schrenk D:
2,3,7,8-Tetrachlorodibenzo-p-dioxin induced cytochrome P450s alter the formation of reactive oxygen species in liver cells. Mol. Nutr. Food Res. 50, 378-384 (2006).

Kunz S, Schwarz M, Schilling B, Päpke O, Lehmler HJ, Robertson LW, Schrenk D and Schmitz HJ:
Tumor promoting potency of PCBs 28 and 101 in rat liver. Toxicol. Lett. 164, 133-143 (2006).

Germer S, Piersma AH, van der Ven L, Kamyschnikow A, Fery Y, Schmitz HJ and Schrenk D:
Subacute effects of the brominated flame retardants hexabromocyclododecane and tetrabromobisphenol A on hepatic cytochrome P450 levels in rats. Toxicology 218, 229-236 (2006).

Baumgart A, Schmidt M, Schmitz HJ and Schrenk D:
Natural furocoumarins as inducers and inhibitors of cytochrome P450 1A1 in rat hepatocytes. Biochem. Pharmacol. 69, 657-667 (2005).

Schmidt M, Schmitz HJ, Baumgart A, Guedon D, Netsch MI, Kreuter MH, Schmidlin CB and Schrenk D:
Cytotoxicity of green tea extracts and their constituents in rat hepatocytes in primary culture. Food Chem. Toxicol. 43, 307-314 (2005).

Schrenk D:
Chemical food contaminants. Bundesges.bl. 47, 841-847 (2004).

Schrenk D, Schmitz HJ, Bohnenberger S, Wagner B and Wörner W:
Tumor promoters as inhibitors of apoptosis in rat hepatocytes. Toxicol. Lett. 149, 43-50 (2004).

Racky J, Schmitz HJ, Kauffmann HM and Schrenk D:
Single nucleotide polymorphism analysis and functional characterization of the human Ah receptor (AhR) gene promoter. Arch. Biochem. Biophys. 421, 91-98 (2004).

Bohnenberger S, Wagner B, Schmitz HJ and Schrenk D:
Inhibition of apoptosis in rat hepatocytes treated with »non-dioxinlike« PCBs. Fres. Environ. Bull. 12, 1-8 (2003).

Conrad S, Kauffmann HM, Ito KI, Leslie EM, Deeley RG, Schrenk D and Cole SPC:
Mutation of Arg⁴³³ in the multidrug resistance protein 1 (MRP1/ABCC1) results in a selective decrease in organic anion transport and in altered drug resistance. Pharmacogenetics 12, 321-330 (2002).

Scheel J, Hussong R, Schrenk D and Schmitz HJ:
Variability of the human aryl hydrocarbon nuclear translocator (ARNT) gene. J. Hum. Gen. 47, 217-224 (2002).

Ostertag E, Becker T, Ammon J, Bauer-Aymanns H and Schrenk D:
Effects of storage conditions on furocoumarin levls in intact, chopped or homogenized parsnips (Pastinaca sativa L.). J. Agr. Food Chem. 50, 2565-2570 (2002).

Kauffmann HM, Pfannschmidt S, Zöller H, Benz A, Vordestemann B, Webster JI and Schrenk D:
Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression. Toxicology 171, 137-146 (2002).

Conrad S, Kauffmann HM, Ito KI, Deeley RG, Cole SPC and Schrenk D:
Identification of human MRP1 mutations and characterization of a G671 V substitution. J. Hum. Gen. 46, 656-663 (2001).

Bohnenberger S, Wagner B, Schmitz HJ and Schrenk D:
Inhibition of apoptosis in rat hepatocytes treated with »non-dioxinlike« polychlorinated biphenyls. Carcinogenesis 22, 1601-1605 (2001).

Zeiger, M., Haag, R., Höckel, J., Schrenk, D. and Schmitz HJ:
Inducing effects of dioxin-like polychlorinated biphenyls on CYP1A1 in the human hepatoblastoma cell line HepG2, the rat hepatoma cell line H4IIE and rat primary hepatocytes - comparison of relative potencies. Tox. Sci. 63, 65-73 (2001).

Kauffmann, H.-M., Vordestemann, B. and Schrenk, D.:
Basal expression of the rat but not the human multidrug resistance protein 2 (MRP2) gene is mediated by CBF/NF-Y and Sp1 promotor binding sites. Toxicology 167, 25-35 (2001).

Wille, G., Mayser, P., Thoma, W., Monsees, T., Baumgart, A., Schmitz, H.-J., Schrenk, D., Polborn, K. and Steglich, W.:
Malassezin - a novel agonist of the arylhydrocarbon receptor from the yeast Malassezia furfur. Bioorg. Med. Chem. 9, 955-960 (2001).

Eneroth, A., Åström, E., Hoogstraate, J., Schrenk, D., Conrad, S., Kauffmann, H.-M. and Gjellan, K.:
Evaluation of a vincristine resistant Caco-2 cell line for use in a Calcein AM extrusion screening assay for P-glycoprotein interaction. Eur. J. Clin. Pharmacol. Sci. 12, 205-214 (2001).

Schrenk, D., Baus, P.R., Ermel, N., Klein, C., Vorderstemann, B. and Kauffman, H.-M.:
Up-regulation of transporters of the MRP family by drugs and toxins. Toxicology Lett. 120, 51-57 (2001).

Conrad, S., Viertelhaus, A., Orzechowski, A., Hoogstraate, J., Gjellan, K., Schrenk, D. and Kauffmann, H.-M.:
Sequencing and tissue distribution of the canine Mrp2 gene compared with Mrp1 and Mdr1. Toxicology 156, 81-91 (2001).

Scheel, J. and Schrenk, D.:
Genomic structure of the human Ah receptor nuclear translocator gene (hARNT). Hum. Genetics 107, 397-399 (2000).

Fiedler, H., Fürst, P., Malisch, R., Päpke, O. and Schrenk, D.:
20th International Symposium on Halogenated Environmental Organic Pollutants & POPs. Environ. Sci. Pollut. Res. 7, 239-242 (2000).

Fromm, M.F., Kauffmann, H.-M., Fritz, P., Burk, O., Kroemer, H.K., Warzok, R.W., Eichelbaum, M., Siegmund, W. and Schrenk, D.:
The effect of rifampin treatment on intestinal expression of human MRP transporters. Am. J. Pathol. 157, 1575-1580 (2000).

Westphal, K., Weinbrenner, A., Zschiesche, M., Franke, G., Knoke, M., Oertel, R., Fritz, P., von Richter, O., Eichelbaum, M., Kauffmann, H.-M., Schrenk, D., Terhaag, B., Kroemer, H.K. and Siegmund, W.:
Induction of P-glycoprotein by rifampicin increases intestinal secretion of talinolol in man: a new type of drug/drug interaction. Clin. Pharmacol. Ther. 68, 345-355 (2000).

van den Berg, M., Peterson, R.E. and Schrenk, D.:
Human risk assessment and TEFs. Food Addit. Contamin. 17, 347-358 (2000).

Dragan, Y.P. and Schrenk, D.:
Animal studies addressing the carcinogenicity of TCDD (or related compounds) with an emphasis on tumour promotion. Food Addit. Contamin. 17, 289-302 (2000).

Schrenk, D., Riebniger, D., Till, M., Vetter, S. and Fiedler, H.-P.:
Tryptanthrins and other tryptophan-derived agonists of the dioxin receptor. Adv. Exp. Med. Biol. 467, 403-408 (2000).

van den Berg, M., van Birgelen, A., Birnbaum, L., Brouwer, B., Carrier, G., Conolly, R., Dragan, Y., Farland, W., Feeley, M., Fürst, P., Galli, C., de Gerlache, J., Grieg, J., Hayashi, Y., Hayashi, Y., Herrman, J., Kogevinas, M., Kurokawa, Larsen, J.C., Y., Liem, D., Luijckx, L., Matsumura, F., McGregor, D., Mocarelli, P., Moore, M., Moy, G., Newhook, R., Ouane, F., Peterson, R., Poellinger, L., Portier, C., Rappe, C., Rogan, W., Schrenk, D., Shkolenok, G., Sweeney, M., Tohyama, C., Tuomisto, J., Ueda, H., Waters, J., , van de Wiel, J., van Leeuwen, F.X.R., Younes, M. and Zeilmaker, M.:
Revison of the tolerable daily intake of dioxin by WHO. Food Add. Contam. 17, 223-240 (2000).

Van Leeuwen, F.X., Feeley, M., Schrenk, D., Larsen, J.C., Farland, W. and Younes, M.:
Dioxins: WHO’s tolerable daily intake (TDI) revisited. Chemosphere 40, 1095-1101 (2000).

Original Research Articles 1995 - 1999

Buchthal, J., Grund, K.E., Buchmann, A., Schrenk, D., Beaune, P. and Bock, K.W.:
Induction of cytochrome P4501A by smoking or omeprazole in comparison with UDP-glucuronosyltransferase in biopsies of human duodenal mucosa. Eur. J. Clin. Pharmacol. 47, 431-435 (1995).

Weber, R., Schrenk, D., Schmitz, H.-J., Hagenmaier, A. and Hagenmaier, H.:
Polyfluorinated dibenzodioxins and dibenzofurans - synthesis, analysis, formation and toxicology. Chemosphere 30, 629-639 (1995).

Schrenk, D., Stüven, T., Gohl, G., Viebahn, R. and Bock, K.W.:
Induction of CYP1A and glutathione S-transferase activities by 2,3,7,8-tetrachlorodibenzo-p-dioxin in human hepatocyte cultures. Carcinogenesis 16, 943-946 (1995).

Schmitz, H.-J., Hagenmaier, A., Hagenmaier, H., Bock, K.W. and Schrenk, D.:
Potency of mixtures of polychlorinated biphenyls as inducers of dioxin receptor-regulated CYP1A activity in rat hepatocytes and H4IIE cells. Toxicology 99, 47-54 (1995).

Orzechowski, A., Schwarz, L.R., Schwegler, U., Bock, K.W., Snyder, R. and Schrenk, D.:
Benzene metabolism in rodent hepatocytes: role of sulfate conjugation. Xenobiotica 25, 1093-1102 (1995).

Schmitz, H.-J., Behnisch, P., Hagenmaier, A., Hagenmaier, H., Bock, K.W. and Schrenk, D.:
CYP1A1-inducing potency in H4IIE cells and chemical composition of technical mixtures of polychlorinated biphenyls. Environ. Toxicol. Pharmacol. 1, 73-79 (1996).

Gohl, G., Lehmköster, T., Münzel, P.A., Schrenk, D., Viebahn, R. and Bock, K.W.:
TCDD-inducible plasminogen activator inhibitor, type 2 (PAI-2) in human hepatocytes, HepG2 and monocytic U937 cells. Carcinogenesis 17, 443-449 (1996).

Wörner, W. and Schrenk, D.:
Influence of 2,3,7,8-tetrachlorodibenzo-p-dioxin on apoptosis in rat hepatocytes initiated by 2-acetylaminofluorene, UV light or transforming growth factor-ß1. Cancer Res. 56, 1272-1278 (1996).

Beck, H., Heinrich-Hirsch, B., Koss, G., Neubert, D., Roßkamp, E., Schrenk, D., Schuster, J., Wölfle, D. and Wuthe, J.:
Anwendbarkeit von 2,3,7,8-TCDD-TEF für PCB für Risikobewertungen. Bundesgesundheitsbl. 39, 141-147 (1996).

Buniatian, G., Gebhardt, R., Schrenk, D. and Hamprecht, B.:
Colocalization of three types of intermediate filament proteins in perisinusoidal stellate cells: glial fibrillary acidic protein as a new cellular marker. Eur. J. Cell Biol. 70, 23-32 (1996).

Schrenk, D.:
Säugerzellkultur-Bioassay zur Erfassung von polychlorierten Dibenzo-p-dioxinen und verwandten Umweltschadstoffen. Bioforum 19, 238-242 (1996).

Schrenk, D., Michalke, A., Gant, T.W., Brown, P.C., Silverman, J.A. and Thorgeirsson, S.S.:
Multidrug resistance gene expression in rodents and rodent hepatocytes treated with mitoxantrone. Biochem. Pharmacol. 52, 1453-1460 (1996).

Schrenk, D., Orzechowski, A., Schwarz, L.R., Snyder, R., Burchell, B., Ingelman-Sundberg, M. and Bock, K.W.:
Phase II metabolism of benzene. Environ. Health Perspect. 104 Suppl. 6, 1183-1188 (1996).

Weber, R., Schmitz, H.-J., Schrenk, D. and Hagenmaier, H.:
Metabolic degradation, inducing potency, and metabolites of fluorinated and chlorinated-fluorinated dibenzodioxins and dibenzofurans. Chemosphere 34, 29-40 (1997).

Schrenk, D., Müller, M., Merlino, G. and Thorgeirsson, S.S.:
Interactions of TCDD with signal transduction and neoplastic development in c-myc transgenic and TGF-alpha transgenic mice. Arch. Toxicol. Suppl. 19, 367-375 (1997).

Silverman, J.A. and Schrenk, D.:
Expression of multidrug resistance genes in the liver. The Hepatic Canalicular Membrane Serial Reviews. FASEB J. 11, 308-313 (1997).

Schmitz, H.-J., Weber, R., Hagenmaier, A., Hagenmaier, H., Poellinger, L. and Schrenk, D.:
2,3,7,8-tetrafluorodibenzo-p-dioxin (TFDD): a potent agonist of the dioxin receptor. Environ. Toxicol. Pharmacol. 3, 105-113 (1997).

Schrenk, D., Riebniger, D., Till, M., Vetter, S. und Fiedler, P.:
Tryptanthrins: a novel class of agonists of the aryl hydrocarbon receptor. Biochem. Pharmacol. 54, 165-171 (1997).

Kauffmann, H.-M., Keppler, D., Kartenbeck, J. und Schrenk, D.:
Induction of multidrug resistance-related protein (Mrp) gene expression in rat hepatocytes. Hepatology 26, 980-985 (1997).

Till, M., Behnisch, P., Hagenmaier, H., Bock, K.W. und Schrenk, D.:
»Dioxinlike« components in incinerator fly ashes: a comparison between chemical analysis data and results from a cell culture bioassay. Environ. Health Perspect. 105, 1326-1332 (1997).

Schrenk, D., Brockmeier, D., Mörike, K., Bock, K.W. und Eichelbaum, M.:
A population study on the distribution of CYP1A2 phenotypes: impact of smoking and oral contraceptives. Eur. J. Clin. Pharmacol. 53, 361-367 (1998).

Weber, R., Hagenmaier, H. und Schrenk, D.:
Elimination kinetics and toxicity of 2,3,7,8-tetrachlorothianthren, a thio analogue of 2,3,7,8-TCDD. Chemosphere 36, 2635-2641 (1998).

Schrenk, D.:
Consequences of »dioxin-type« induction of drug-metabolizing enzymes for the metabolism of endo- and xenobiotics – a commentary. Biochem. Pharmacol. 55, 1155-162 (1998).

Kauffmann, H.-M. und Schrenk, D.:
Sequence analysis and functional characterization of the 5'-flanking region of the rat multidrug resistance protein 2 (MRP2) gene. Biochem. Biophys. Res. Commun. 245, 325-331 (1998).

Riebniger, D. und Schrenk, D.:
Non-responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of transforming growth factor-ß1 (TGF-ß1) and CYP1A1 gene expression in rat liver fat-storing cells. Toxicol. Appl. Pharmacol. 152, 251-260 (1998).

Van den Berg, M., Birnbaum, L., Bosveld, A.T.C., Brunstrom, B., Cook, P., Feeley, M., Giesy, J.P., Hanberg, A., Hasegawa, R., Kennedy, S.W., Kubiak, T., Larsen, J.C., van Leeuwen, F.X.R., Liem, A.K.D., Nolt, C., Peterson, R.E., Poellinger, L., Safe, S., Schrenk, D., Tillitt, D., Tysklind, M., Younes, M., Waern, F. A und Zacharewski, T.:
Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ. Health Perspect. 106, 775-792 (1998).

Kauffmann, H.-M., Keppler, D., Gant, T.M. und Schrenk, D.:
Induction of hepatic mrp2 (cmrp/cmoat) gene expression in nonhuman primates treated with rifampicin or tamoxifen. Arch. Toxicol. 72, 763-768 (1998).

Wörner, W. und Schrenk, D.:
2,3,7,8-Tetrachlorodibenzo-p-dioxin suppresses apoptosis and leads to hyperphosphorylation of p53 in rat hepatocytes. Environ. Toxicol. Pharmacol. 6, 239-247 (1998).

Till, M., Riebniger, D., Schmitz, H.-J. und Schrenk, D.:
Potency of various polycyclic aromatic hydrocarbons as inducers of CYP1A1 in rat hepatocyte cultures. Chem.-Biol. Interact. 117, 135-150 (1999).

Schrenk, D. und Fürst, P.:
Neufestsetzung der duldbaren täglichen Aufnahme an Dioxinen durch die WHO. Nachr. Chemie Techn. Labor. 47, 313-316 (1999) .

Schrenk, D. und Fürst, P.:
Ableitung der tolerierbaren täglichen Dioxin-Aufnahme durch die WHO. Umweltmed. Forsch. Prax. 4, 163-167 (1999).

Schrenk, D. und Fürst, P.: Der belgische Dioxin-Skandal – Ursachen und gesundheitliche Relevanz. Umweltmed. Forsch. Prax. 6, 317-322 (1999).

Book Chapters

Kunz, W., Schwarz, M., Schrenk, D., Stöckle, G. und Remmer, H.:
The paradoxical action of phenobarbital on the metabolism of dimethylnitrosamine. In: Biochemistry, Biophysics and Regulation of Cytochrome P-450, Dev. in Biochem. 13 (Gustafsson, J.-A., Carlstadt-Duke, J., Mode, A., and Rafter, J. eds), Elsevier/North-Holland, New York, pp. 259-261 (1980).

Schrenk, D., Schwarz, M., Tennekes, H. und Kunz, W.:
A novel pathway of nitrosamine metabolism in liver microsomes: denitrosation of nitrosamines by cytochrome P-450. In: Advances in Experimental Medicine and Biology 136 B (Snyder, R., Parke, D.V., Kocsis, J.J., Jollow, D.J., Gibson, C.G., and Witmer, C.M. eds.), Plenum Press, London & New York, pp. 1157-1164 (1982).

Schrenk, D. und Bisswanger, H.:
ESR measurements with the pyruvate dehydrogenase complex from Escherichia coli. In: Proceedings of the 16th FEBS Congress (Ovchinnikov, Y.A. ed.), VNU Science Press, Utrecht, pp. 89-94 (1984).

Dekant, W., Vamvakas, S., Berthold, K., Schrenk, D., Schmidt, S. und Henschler, D.:
Cysteine conjugates of halogenated alkenes: their formation, cleavage and mutagenicity. In:Primary Changes and Control Factors in Carcinogenesis (Friedberg, T. and Oesch, F. eds.), Deutscher Fachschriften Verlag, Wiesbaden, pp. 72-75 (1986).

Bisswanger, H., Horn, F. und Schrenk, D.:
Thiamin Pyrophosphate Biochemistry, Vol. II, CRC Press, Boca Raton, USA, pp. 63-75 (1988).

Bock, K.W., Kobusch A.-B., Lipp, H.-P., Münzel, P.A., Röhrdanz, E., Schrenk, D. und Eriksson, L.C.:
Regulation of rat phenol UDP-glucuronosyltransferase and its persistently increased expression at liver cancer prestages. In: Hepatic Metabolism and Disposition of Endo- and Xenobiotics (Bock, K.W., Gerok, W., Matern, S. und Schmid R. eds.) Kluwer Acad. Publ. Dordrecht, Boston, London, pp. 217-228 (1991).

Schrenk, D.:
Polychlorierte Biphenyle. In: Praktische Umweltmedizin, (Beyer, A. und Eis, E., Hrsg.), Springer-Verlag, Heidelberg (1994), zweite, überarbeitete Fassung (2004).

Schrenk, D.:
Benzol. In: Praktische Umweltmedizin, (Beyer, A. und Eis, E., Hrsg.), Springer-Verlag, Heidelberg (1994).

Schrenk, D., Gant, T.W., Silverman, J.A., Preisegger, K. und Thorgeirsson, S.S.:
Induction of multidrug resistance gene products in cholestasis. In: Transport in the Liver (Keppler, D. und Jungermann, K., eds.), Kluwer Acad. Publ. Dordrecht, Boston, London, pp. 243-252 (1994).

Schrenk, D.:
Moderne Aspekte der Gentherapie - Chancen und Risiken. In: Schriftenreihe »Arbeitshilfen« der Pädagogischen Arbeitsstelle für Erwachsenenbildung in Baden-Württemberg, Stuttgart (1996).

Schrenk, D.:
Experimental Systems. In: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 69, Polychlorinated Dibenzo-p-dioxins and Polychlorinated Dibenzofurans, IARC, Lyon (1997).

Schrenk, D.:
Kohlenwasserstoffe. In: Umweltmedizin/Ökologische Medizin (Mersch-Sundermann, V., Hrsg.), Thieme-Verlag, Stuttgart (1999).

Schrenk, D.:
Niedermolekulare Organohalogene. In: Umweltmedizin/Ökologische Medizin (Mersch-Sundermann, V., Hrsg.), Thieme-Verlag, Stuttgart (1999).

Schrenk, D.:
Experimental Systems. In: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 71, Re-Evaluation of some Organic Chemicals, Hydrazine and Hydrogen Peroxide, IARC, Lyon (1999).

Schrenk, D., Fürst, P.:
Ableitung der tolerierbaren täglichen Dioxin-Aufnahme durch eine Expertengruppe der WHO. In: Gefährdungsabschätzung von Umweltschadstoffen. Ergänzbares Handbuch toxikologischer Basisdaten und ihre Bewertung (Eikmann, T., Heinzow, B., Konietzka, R., Hrsg.), Erich Schmidt Verlag, Berlin (1999).

Wörner, W., Müller, M., Schmitz, H.-J. und Schrenk, D.:
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses apoptosis in the livers of c-myc transgenic mice and in rat hepatocytes in primary culture. In: Carcinogenic and Anticarcinogenic Factors in Food (Eisenbrand, G., Dayan, A.D., Elias, P.S., Grunow, W. und Schlatter, J., Hrsg.), Wiley-VCH, Weinheim (2000).

Fürst, P. und Schrenk, D.:
Dioxine. In: Enzyklopädie Naturwissenschaft und Technik, ecomed-Verlag, Landsberg, (2000).

Schrenk, D.:
Unbedenklichkeitsgrenzen bei Lebensmittelinhaltsstoffen (upper intake levels). In: Funktionelle Lebensmittel - Lebensmittel der Zukunft (Lebensmittelchemische Gesellschaft, Hrsg.). Behr’s Verlag, Hamburg (2000).

Koss, W., Schrenk, D., Wölfle, D.:
Halogenierte polyzyklische Kohlenwasserstoffe. In: Lehrbuch der Toxikologie (Marquardt, H., Schäfer S., Hrsg), 2. Auflg., Spektrum-Verlag, Heidelberg (2004).

Schrenk, D.
(vorm. Seeger, I., Neumann, H.-G.): Giftlexikon. Deutscher Apotheker-Verlag, Stuttgart, laufende Ergänzungen.

Schrenk, D.:
Toxikodynamik-Tests. In: Regulatorische Toxikologie (Reichl, F.-X., Schwenk, M., Hrsg.)Springer-Verlag, Heidelberg (2004).

Schrenk, D.:
Host factors relevant for bioavailability: Transporters, metabolic enzymes and genetic polymorphisms. In: Functional Food: Safety Aspects (Eisenbrand, G., Hrsg.) Wiley-VCH (2004).

Original Research Articles since 2000

Original Research Articles 1995 - 1999

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