Research Group Deponte

Teaching & Tools

of the Deponte lab

News: Teaching update!

The courses "Vergleichende Biochemie" and "Enzymology" of the WS2020 will be held online in real-time using skype4business. The courses will not be provided as asynchronous screencasts or ghost lectures due to the interactive teaching concept. If you want to participate in the courses, please contact the secretary Frau Fluck and me before October the 26th. Skype4business is available for students with a rhrk account (for more information and download See here).

Online Tools

Lectures & Seminars

Protein biochemistry (German)

Lecturer: M. Deponte

Course: See here

Term: Summer semester

 

Venue & Time:

HS 52-207 / Mon 845 - 930 

HS 52-204 / Tue 900 - 1030

 

Content:

  • Advanced amino acid metabolism (rep. proteinogenic amino acids, enzyme mechanisms, connections with carbon metabolism, mediators/hormons/neurotransmitters, nitrogen excretion)
  • Protein structure (rep. primary to quaternary structure, folding problem, structure-function relationships)
  • Intracellular protein turnover (synthesis, folding, sorting, secondary modifications, degradation)
  • Protein production and purification (methods in research & industry)

 

Material:

Vorlesung 1 (Aminosäuremetabolismus)

Vorlesung 2 (Aminosäuremetabolismus)

Seminar 1 (Aminosäuremetabolismus)

Vorlesung 3 (Aminosäuremetabolismus)

Seminar 2 (Proteinstruktur)

Vorlesung 4 (Proteinstruktur)

Seminar 3 (Proteinstruktur)

Vorlesung 5 (Proteinumsatz)

Seminar 4 (Proteinumsatz)

Vorlesung 6 (Proteinumsatz)

Seminar 5 (Proteinumsatz)

Vorlesung 7 (Proteinumsatz)

Vorlesung 8 (Proteinumsatz)

Seminar 6 (Proteinumsatz)

Vorlesung 9 (Proteinumsatz)

Seminar 7 (Proteinumsatz)

Vorlesung 10 (Proteinumsatz)

Vorlesung 11 (Proteinreinigung)

Seminar 8 (Proteinreinigung)

Vorlesung 12 (Proteinreinigung)

Seminar 9 (Proteinreinigung)

 

Tests:

Nachholklausur Proteinbiochemie 25.10.2018

Klausur Proteinbiochemie 15.07.2019

Nachholklausur Proteinbiochemie 29.10.2019

Klausur Proteinbiochemie 15.07.2020

Mol. parasitology / Microbial biochem. II (Engl.)

Lecturer: M. Deponte

Course: See here

Term: Summer semester

 

Venue & Time:

To be announced 

 

Content:

  • Overview and phylogeny of parasitic protists
  • Special cell organelles and metabolic pathways
  • Molecular parasitology
  • Drug development (screening vs. rational drug design, target identification)
  • Resistance mechanisms

 

Material:

Lecture 1

Lecture 2

Lecture 3

Lecture 4

Lecture 5

Lecture 6

Lecture 7

Lecture 8

 

Tests:

Oral test for groups < 8 persons

Comparative biochemistry (German)

Lecturer: M. Deponte

Course: See here

Term: Winter semester

 

Venue & Time:

HS 52-204 / Mon 1145 - 1315 

HS 46-280 / Wed 845 - 930

 

Content:

  • Introduction (organismic diversity, metabolic compartmentalization)
  • Comparison of metabolic pathways (examples of analogous & differing reactions, purine and pyrimidine metabolism)
  • Model systems and applications (eukaryotic and prokaryotic model systems, molecular tools)
  • Comparison of pro- and eukaryotes (energy metabolism, information systems, growth and reproduction, optional: defence & immune systems or motility)

 

Material:

Vorlesung 1 (Einführung)

Vorlesung 2 (Einführung)

Vorlesung 3 (Einführung)

Vorlesung 4 (Vergleich von Stoffwechselwegen)

Vorlesung 5 (Vergleich von Stoffwechselwegen)

Vorlesung 6 (Vergleich von Stoffwechselwegen)

Vorlesung 7 (Vergleich von Stoffwechselwegen)

Vorlesung 8 (Modellsysteme und Anwendungen)

Vorlesung 9 (Modellsysteme und Anwendungen)

Vorlesung 10 (Modellsysteme und Anwendungen)

Vorlesung 11 (Modellsysteme und Anwendungen)

Vorlesung 12 (Vergleich Pro- und Eukaryoten)

Seminar 1 (Proteinvisualisierung)

Seminar 2 (Proteinvisualisierung)

Seminar 3 (Proteinvergleich)

Seminar 4 (Lipidrepetitorium)

Seminar 5 (Kohlenhydratrepetitorium)

Seminar 6 (Basenrepetitorium)

Seminar 7 (Modellsysteme und Anwendungen)

Seminar 8 (Modellsysteme und Anwendungen)

Seminar 9 (Modellsysteme und Anwendungen)

Seminar 10 (Modellsysteme und Anwendungen)

Seminar 11 (Vergleich Pro- und Eukaryoten)

 

Tests:

Nachholklausur vergleichende Biochemie 16.05.2018

Klausur vergleichende Biochemie 13.03.2019

Nachholklausur vergleichende Biochemie 17.05.2019

Klausur vergleichende Biochemie 22.05.2020

Enzymology (Engl.)

Lecturer: M. Deponte

Course: See here

Term: Winter semester

 

Venue & Time:

Room 54-656 / Tue 900 - 1045 

 

Content:

  • Enzyme classification
  • Principles of enzyme catalysis
  • Steady-state and pre-steady state kinetics
  • Reversible and irreversible reactions
  • Enzyme inhibitors
  • Allostery and cooperativity
  • Data analysis and evaluation
  • Selected enzyme mechanisms and examples

 

Material:

Lecture 1

Lecture 2

Lecture 3

Lecture 4

Lecture 5

Lecture 6

Lecture 7

Kinetic data excercise

 

Tests:

Klausur Enzymology 05.02.2019

Klausur Enzymology 17.02.2020

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