Teaching & Tools
of the Deponte lab
News: Teaching update!
Depending on the availability of lecture halls and official regulations, the courses "Vergleichende Biochemie" and "Enzymology" of the WS2020 will be held either face-to-face or online in real-time using skype4business. The courses will not be provided as asynchronous screencasts or ghost lectures due to the interactive teaching concept. If you want to participate in the courses, please contact the secretary Frau Fluck and me before October the 26th. Skype4business is available for students with a rhrk account (for more information and download See here).
Online Tools
Data analysis:
Protocols:
Literature:
Lectures & Seminars
Protein biochemistry (German)
Lecturer: M. Deponte
Course: See here
Term: Summer semester
Venue & Time:
HS 52-207 / Mon 845 - 930
HS 52-204 / Tue 900 - 1030
Content:
- Advanced amino acid metabolism (rep. proteinogenic amino acids, enzyme mechanisms, connections with carbon metabolism, mediators/hormons/neurotransmitters, nitrogen excretion)
- Protein structure (rep. primary to quaternary structure, folding problem, structure-function relationships)
- Intracellular protein turnover (synthesis, folding, sorting, secondary modifications, degradation)
- Protein production and purification (methods in research & industry)
Material:
Vorlesung 1 (Aminosäuremetabolismus)
Vorlesung 2 (Aminosäuremetabolismus)
Seminar 1 (Aminosäuremetabolismus)
Vorlesung 3 (Aminosäuremetabolismus)
Vorlesung 11 (Proteinreinigung)
Vorlesung 12 (Proteinreinigung)
Tests:
Nachholklausur Proteinbiochemie 25.10.2018
Klausur Proteinbiochemie 15.07.2019
Mol. parasitology / Microbial biochem. II (Engl.)
Lecturer: M. Deponte
Course: See here
Term: Summer semester
Venue & Time:
To be announced
Content:
- Overview and phylogeny of parasitic protists
- Special cell organelles and metabolic pathways
- Molecular parasitology
- Drug development (screening vs. rational drug design, target identification)
- Resistance mechanisms
Material:
Tests:
Oral test for groups < 8 persons
Comparative biochemistry (German)
Lecturer: M. Deponte
Course: See here
Term: Winter semester
Venue & Time:
HS 52-204 / Mon 1145 - 1315
HS 46-280 / Wed 845 - 930
Content:
- Introduction (organismic diversity, metabolic compartmentalization)
- Comparison of metabolic pathways (examples of analogous & differing reactions, purine and pyrimidine metabolism)
- Model systems and applications (eukaryotic and prokaryotic model systems, molecular tools)
- Comparison of pro- and eukaryotes (energy metabolism, information systems, growth and reproduction, optional: defence & immune systems or motility)
Material:
Vorlesung 4 (Vergleich von Stoffwechselwegen)
Vorlesung 5 (Vergleich von Stoffwechselwegen)
Vorlesung 6 (Vergleich von Stoffwechselwegen)
Vorlesung 7 (Vergleich von Stoffwechselwegen)
Vorlesung 8 (Modellsysteme und Anwendungen)
Vorlesung 9 (Modellsysteme und Anwendungen)
Vorlesung 10 (Modellsysteme und Anwendungen)
Vorlesung 11 (Modellsysteme und Anwendungen)
Vorlesung 12 (Vergleich Pro- und Eukaryoten)
Seminar 1 (Proteinvisualisierung)
Seminar 2 (Proteinvisualisierung)
Seminar 5 (Kohlenhydratrepetitorium)
Seminar 7 (Modellsysteme und Anwendungen)
Seminar 8 (Modellsysteme und Anwendungen)
Seminar 9 (Modellsysteme und Anwendungen)
Seminar 10 (Modellsysteme und Anwendungen)
Seminar 11 (Vergleich Pro- und Eukaryoten)
Tests:
Nachholklausur vergleichende Biochemie 16.05.2018
Klausur vergleichende Biochemie 13.03.2019
Enzymology (Engl.)
Lecturer: M. Deponte
Course: See here
Term: Winter semester
Venue & Time:
Room 54-656 / Tue 900 - 1045
Content:
- Enzyme classification
- Principles of enzyme catalysis
- Steady-state and pre-steady state kinetics
- Reversible and irreversible reactions
- Enzyme inhibitors
- Allostery and cooperativity
- Data analysis and evaluation
- Selected enzyme mechanisms and examples
Material:
Tests: