Arbeitsgruppe Schrenk


Ufelmann, H.; Schrenk, D. (2015) Nodularin-triggered apoptosis and hyperphosphorylation of signaling proteins in cultured rat hepatocytes. Toxicology in Vitro [Online], 29 (1), 16–26.

Berg, K., Braun, C., Krug, I., Schrenk, D. (2015). Evaluation of the cytotoxic and mutagenic potential of three ginkgolic acids. Toxikology, Volume 327, 47-52.

Larsson, M., van den Berg, M., Brenerová, P., van Duursen, M.B., van Ede, K.I., Lohr, C., Luecke-Johansson, S., Machala, M., Neser, S., Pěnčíková, K., Poellinger, L., Schrenk, D., Strapáčová, S., Vondráček, J., Andersson, P.L. (2015). Consensus toxicity for polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls combining in silico models and extensive in vitro screening of AhR-mediated effects in human and rodent cells. Chem Res Toxicol., 28(4), 641-650.

Zhang, Y., Fraatz, M. A., Müller, J., Schmitz, H.-J., Birk, F., Schrenk, D., Zorn, H. (2015). Aroma Characterization and Safety assessment of a Beverage Fermented by Trametes versicolor. J. Agric. Food Chem., 63(31), 6915-6921.

Cartus, A. T., Stegmüller, S., Simson, N., Wahl, A., Neef, S., Kelm, H., Schrenk, D. (2015). Hepatic metabolism of carcinogenic β-asarone. Chem. Res. Toxicol., 28(9), 1760-1773.



Budinsky, R. A., Schrenk, D., Simon, T., Van den Berg, M., Reichard, J. F., Silkworth, J. B., ... & Rowlands, J. C. (2013). Mode of action and dose-response framework analysis for receptor-mediated toxicity: the aryl hydrocarbon receptor as a case study. Critical reviews in toxicology, 44(1), 83-119.

Viluksela, M., Heikkinen, P., van der Ven, L. T., Rendel, F., Roos, R., Esteban, J., ... & Håkansson, H. (2014). Toxicological Profile of Ultrapure 2, 2′, 3, 4, 4′, 5, 5′-Heptachlorbiphenyl (PCB 180) in Adult Rats. PloS one, 9(8), e104639.

Anger, L. T., Wolf, A., Schleifer, K. J., Schrenk, D., & Rohrer, S. G. (2014). Generalized Workflow for Generating Highly Predictive in Silico Off-Target Activity Models. Journal of chemical information and modeling, 54(9), 2411-2422.

Raquet, N., & Schrenk, D. (2014). Application of the equivalency factor concept to the phototoxicity and–genotoxicity of furocoumarin mixtures. Food and Chemical Toxicology, 68, 257-266.

Herrmann, K., Engst, W., Meinl, W., Florian, S., Cartus, A. T., Schrenk, D., ... & Glatt, H. (2014). Formation of hepatic DNA adducts by methyleugenol in mouse models: drastic decrease by Sult1a1 knockout and strong increase by transgenic human SULT1A1/2. Carcinogenesis, 35(4), 935-941.



Gährs, M., Roos, R., Andersson, P. L., & Schrenk, D. (2013). Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes. Toxicology and applied pharmacology, 272(1), 77-85.

Merz, K. H., Jochims, K., & Schrenk, D. (2013). Risk assessment based on computer-aided and bibliographical methods of a homeopathic preparation from Pulsatilla pratensis L. as an example. Toxicology Letters, 221, 228.

van den Berg, M., Denison, M. S., Birnbaum, L. S., DeVito, M. J., Fiedler, H., Falandysz, J., ... & Peterson, R. E. (2013). Polybrominated dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds. Toxicological Sciences, 133(2), 197-208.

Schrenk, D., Merz, K. H., & Jochims, K. (2013). Feasibility study of nonclinical safety assessments on homeopathic preparations using the example of protoanemonin in Pulsatilla pratensis L. Regulatory Toxicology and Pharmacology, 66(1), 104-108.

Solecki, G. M., Groh, I. A. M., Kajzar, J., Haushofer, C., Scherhag, A., Schrenk, D., & Esselen, M. (2013). Genotoxic Properties of Cyclopentenone Prostaglandins and the Onset of Glutathione Depletion. Chemical research in toxicology, 26(2), 252-261.

Hausinger, K., Lipps, M., Raddatz, H., Rosch, A., Rudy, H., Scholten, G., & Schrenk, D. (2013). Automated optical grape sorting: influence of grape rot on the contents of biogenic amines in musts and wines of the vintages 2010 and 2011. Mitteilungen Klosterneuburg, Rebe und Wein, Obstbau und Früchteverwertung, 63(2), 70-78.



Hausinger, K., Raddatz, H., Rudy, H., Scholten, G., & Schrenk, D. (2012). Optimized Method for the Quantification of the most important Polyphenols in White Wine by means of HPLC and UV-Detection. DEUTSCHE LEBENSMITTEL-RUNDSCHAU, 108(12), 635–638.

Cartus, A. T., Herrmann, K., Weishaupt, L. W., Merz, K.-H., Engst, W., Glatt, H., & Schrenk, D. (2012). Metabolism of methyleugenol in liver microsomes and primary hepatocytes: pattern of metabolites, cytotoxicity, and DNA-adduct formation. Toxicological sciences : an official journal of the Society of Toxicology, 129(1), 21–34.

Cartus, A. T., Herrmann, K., Groh, I., Weishaupt, L. W., Merz, K. H., Engst, W., ... & Schrenk, D. (2012). Toxicological properties of methyleugenol and methylisoeugenol metabolites. Toxicology Letters, 211, 96.

Esselen, M., Solecki, G. M., Kajzar, J., & Schrenk, D. (2012). Genotoxic effects of cyclopentenone prostaglandins in hamster lung fibroblast cells. Toxicology Letters, 211, 65–66.

Roos, R., Rendel, F., Herlin, M., Hamscher, G., Halldin, K., Schrenk, D., ... & Viluksela, M. (2012). Toxicological profiles of two abundant PCBs in rat offspring. Toxicology Letters, 211, S85-S86.

Schrenk, D. (2012). Dose-response relationship in toxicity following Ah receptor activation. Toxicology Letters, 211, 22.

Groh, I. A. M., Cartus, A. T., Vallicotti, S., Kajzar, J., Merz, K. H., Schrenk, D., & Esselen, M. (2012). Genotoxic potential of methyleugenol and selected methyleugenol metabolites in cultured Chinese hamster V79 cells. Food & function, 3(4), 428–436.

Ufelmann, H., Krüger, T., Luckas, B., & Schrenk, D. (2012). Human and rat hepatocyte toxicity and protein phosphatase 1 and 2A inhibitory activity of naturally occurring desmethyl-microcystins and nodularins. Toxicology, 293(1), 59-67.

Messer, A., Raquet, N., Lohr, C., & Schrenk, D. (2012). Major furocoumarins in grapefruit juice II: Phototoxicity, photogenotoxicity, and inhibitory potency vs. cytochrome P450 3A4 activity. Food and Chemical Toxicology, 50(3), 756–760.

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