| TU Kaiserslautern > Fachbereich Chemie > Lebensmittelchemie & Toxikologie > AK Eisenbrand > Publikationen | Impressum |
Publikationen - Zeitschriften
2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995
| Genotoxicity of glycidamide in comparison to (+/-)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide
and alpha-acetoxy-N-nitroso-diethanolamine in human blood and V79-cells
Thielen S., Baum M., Hoffmann M., Loeppky R.N., Eisenbrand G. Molecular Nutrition and Food Research 2005, accepted |
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| Modulation of oxidative celo damage by polyphenolic apple juice
extracts and major consitutents in human colon cells Schaefer S., Baum M., Eisenbrand G., Dietrich H., Will F., Janzowski C. Molecular Nutrition and Food Research 2005, submitted |
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| Molecular targets of indirubins Jakobs S., Merz K.-H., Vatter S., Eisenbrand G. International Journal of Clinical Pharmacology and Therapeutics 2005, 43 (12), 592-594 |
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| Searching for cellular targets of novel pteridines downstream of
cAMP PDE inhibition Vatter S., Merz K.-H., Eisenbrand G. International Journal of Clinical Pharmacology and Therapeutics 2005, 43 (12), 607-608 |
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| Natural flavonoids are potent inhibitors of glycogen phosphorylase
Jakobs S., Fridrich D., Hofem S., Pahlke G., Eisenbrand G. Molecular Nutrition and Food Research 2005, in press |
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| Ochratoxin A induces oxidative DNA damage in liver and kidney after
oral dosing to rats Kamp H.G., Eisenbrand G., Janzowski C., Kiossev J., Latendresse J.R., Schlatter J., Turesky R.J. Molecular Nutrition and Food Research 2005, 49, 1160-1167 |
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| Indirubin-3’-Aminooxy-Acetate inhibtis Glycogen Phosphorylase by
Binding at the Inhibitor and the Allosteric Site. Broad Specificities
of the Two Sites Kosmopoulou M.N., Leonidas D.D., Chrysina E.D., Eisenbrand G., Oikonomakos N.G. Letters in Drug Design & Discovery 2005, 2, 377-390 |
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| Indirubin derivatives inhibit Stat3 signaling and induce apoptosis
in human cancer cells Nam S., Buettner R., Turkson J., Kim D., Cheng J.Q., Muehlbeyer S., Hippe F., Vatter S., Merz K.-H., Eisenbrand G., Jove R. PNAS 2005, 102 (17), 5998-6003 |
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| Differential phosphodiesterase expression and cytosolic Ca2+ in
human CNS tumour cells and in non-malignant and malignant cells of
rat origin. Vatter S., Pahlke G., Deitmer J.W., Eisenbrand G. Journal of Neurochemistry 2005, 95, 321-329 |
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| From the insoluble dye indirubin towards highly active, soluble
CDK2-inhibitors. Jautelat R., Brumby T., Schäfer M., Briem H., Eisenbrand G., Schwahn S., Krüger M., Lücking U., Prien O., Siemeister G. ChemBioChem 2005, 6 (3), 531-540 |
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| Ochratoxin A: Induction of (oxidative) DNA damage, cytotoxicity
and apoptosis in mammalian cell lines and primary cells. Kamp H.G., Eisenbrand G., Schlatter J., Würth K., Janzowski C. Toxicology 2005, 206, 413-425 |
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| Inhibition of GSK3ß by indirubins restores HIF-i? accumulation under
prolonged periods of hypoxia/anoxia. Schnitzer S.E., Schmid T., Zhou J., Eisenbrand G., Brüne B. FEBS Letters 2005, 579, 529-533 |
| Criteria for the evaluation of functional foods Eisenbrand G. Molecular Nutrition and Food Research 2004, 48, 541-544 |
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| Acrylamide and glycidamide: genotoxic effects in V79-cells and human blood Baum M., Fauth E., Fritzen S., Hermann A., Mertes P., Merz K.-H., Rudolphi M., Zankl H., Eisenbrand G. Toxicology 2004, 580, 61-69 |
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| Novel indirubin derivatives, promising antitumor agents inhibiting
cyclin-dependent kinases. Merz K.H., Schwahn S., Hippe F., Mühlbeyer S., Jakobs S., Eisenbrand G. International Journal of Clinical Pharmacology and Therapeutics 2004, 42 (11), 656-658 |
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| Effects of hemodialysis, dialyser type and iron infusion on oxidative
stress in uremic patients. Müller C., Eisenbrand G., Gradinger M., Rath T., Albert F.W., Vienken J., Singh R., Farmer P.B., Stockis J.-P., Janzowski C. Free Radical Research 2004, 38 (10), 1093-1100 |
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| Molecular mechanisms of indirubin and its derivatives: novel anticancer molecules
with their origin in traditional Chinese phytomedicine. Eisenbrand G., Hippe F., Jakobs S., Mühlbeyer S. Journal of Cancer Research and Clinical Oncology 2004, 130, 627-635 |
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| Inhibition of Leishmania mexicana CRK3 Cyclin-Dependent Kinase:
Chemical Library Screen and Antileishmanial Activity. Grant K.M., Dunion M.H., Yardley V., Skaltsounis A.-L., Marko D., Eisenbrand G., Croft S.L., Meijer L., Mottram J.C. Antimicrobial Agents and Chemotherapy 2004, 48 (8), 3033-3042 |
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| Sensitive in vitro test systems to determine androgenic/antiandrogenic
activity Guth S.E., Böhm S., Mu&sßler B.H., Eisenbrand G. Mol. Nutr. Food Res. 2004, 48 (4) , 282-291 |
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| Binding of the potential antitumour agent indirubin-5-sulphonate at
the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison
with ligand binding to pCDK2-cyclin A complex. Kosmopoulou M.N., Leonidas D.D., Chrysina E.D., Bischler N., Eisenbrand G., Sakarellos C.E., Pauptit R., Oikonomakos N.G. Eur. J. Biochem., FEBS 2004, 271, 2280-2290 |
| Alpha, beta-unsaturated carbonyl compounds: induction of oxidative
DNA damage in mammalian cells C. Janzowski, V. Glaab, C. Müller, U. Strässer, H.G. Kamp, G. Eisenbrand Mutagenesis 2003, 18 (5), 465-470 |
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| Synthesis of N-Acetyl-S-(3-coumarinyl)-cysteine Methyl Ester and
HPLC Analysis of Urinary Coumarin Metabolites Eisenbrand G., Michael Otteneder, W.C. Tang Toxicology 2003, 190, 249-258 |
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| Mutagenic and cytotoxic effectiveness of diisopropyl xanthogen polysulphide
in human lymphocyte cultures. V. Zensen, T.M. Ali, M. Kuproth, H. Zankl, C. Janzowski, G. Esenbrand Mutat Res 2003, 535, 161-170 |
| Intracellular localization of 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidino-pteridine
in membrane structures impeding the inhibition of cytosolic cyclic
AMP-specific phosphodiesterase Doris Marko, Karl-Heinz Merz, Claudia Kunz, Anja Müller, Nadya Tarasova, Gerhard Eisenbrand Biochemical Pharmacology 2002, 63, 669-676 |
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| 7-Benzylamino-6-chloro-2-piperazino-4-pyrrolidino-pteridine, a potent
inhibitor of cAMP-specific phosphodiesterase, enhancing nuclear protein
binding to the CRE consensus sequence in human tumour cells Barbara Wagner, Sandra Jakobs, Michael Habermeyer, Frankie Hippe, Yoon Sang Cho-Chung, Gerhard Eisenbrand, Doris Marko Biochemical Pharmacology 2002, 63, 659-668 |
| Mutagenic and cytotoxic effectiveness of zinc dimethyl and zinc
diidononyldithiocarbamte in human lymphocyte cultures V. Zensen, E. Fauth, H. Zankl, C. Janzowski, G. Eisenbrand Mutation Research 2001, 497, 89-99 |
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| DNA damaging potential and glutathione depletion of 2-cyclohexene-1-one
in mammalian cells, compared to food relevant 2-alkenals Volker Glaab, Andrew R. Collins, Gerhard Eisenbrand, Christine Janzowski Mutation Research 2001, 497, 185-197 |
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| Lycobetaine acts as a selective topoisomerase IIbeta poison and
inhibits the growth of human tumor cells. Hans Ullrich Barthelems, Ellen Niederberger, Thomas Roth, Kerstin Schulte, Wei Ci Tang, Fritz Boege, Heinz-H. Fiebig, Gerhard Eisenbrand, Doris Marko British Journal of Cancer 2001, 85 (10), 1585-1591 |
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| Inhibitor Binding to Active and Inactive CDK2: The Crystal Structure
of CDK2-Cyclin A/Indirubin-5-Sulphona Thomas G. Davies, Paul Tunnah, Laurent Meijer, Doris Marko, Gerhard Eisenbrand, Jane A. Endicott, Martin E.M. Noble Structure 2001, Vol. 9, 389-397 |
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| Anti-mitotic properties of indirubin-3'-monoxime, a CDK/GSK-3 inhibiotr:
induction of endoreplicatin following prophase arrest E. Damiens, B. Baratte, D. Marie, G. Eisenbrand, L. Meijer Oncogene 2001, 20, 3786-3797 |
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| Metabolic Activation of Benzo(c)phenanthrene by Cytochrome P450
Enzymes in Human Liver and Lung M. Baum, S. Amion, F.P. Guengerich, S.S. Hecht, W. Köhl, G. Eisenbrand Chemical Research in Toxicology 2001, Vol. 14, Number 6, 686-693 |
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| Indirubins inhibit glycogen synthase kinase–3beta and CDK/p25,
two protein kinases involved in abnormal tau phosphorylation in Alzheimer’s
disease – A property common to most CDK inhibitors? S. Leclerc, M. Garnier, R. Hoessel, D. Marko, J.A. Bibb, G.L. Snyder, P. Greengard, J. Biernat, E.-M. Mandelkow, G. Eisenbrand, L. Meijer Journal of Biological Chemistry 2001, 276 (1), 251-260 |
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| Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives
in human tumor cells D. Marko, S. Schätzle, A Friedel, E. Niederberger, A Genzlinger, H. Zankl, L Meijer, G. Eisenbrand British Journal of Cancer 2001, 84 (2), 283-289 |
| Kombinationswirkungen hormonartig wirkender Chemikalien G.Eisenbrand, B. Mußler, G. Degen Arbeitsphysiologie heute 2000, 2, 27-39 |
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| 5-Hydroxymethylfurfural: Assessment of mutagenicity, DNA damaging
potetial and reactivity towards cellular glutathione C. Janzowski, V. Glaab, E. Samimi, J. Schlatter, G. Eisenbrand Food and Chemical Toxicology 2000, 38, 801-809 |
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| Cyclic 3’,5’-Nucleotide Phosphodiesterases: Potential
Targets for Anticancer Therapy D. Marko, G. Pahlke, K.-H. Merz, G. Eisenbrand Chem. Res. Tox. 2000, 13, 944-948 |
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| Estimation of Human Exposure to Styrene and Ethylbenzene W. Tang, I. Hemm G. Eisenbrand Toxicology 2000, 144, 39-50 |
| Indirubin, the active constituent of a Chinese antileukeamia medicin,
inhibits cyclin-depentent kinases R. Hössel, S. Leclerc, J.A. Endicott, M.E.M.Nobel, A. Lawrie, P Tunnah, M Leost, E. Damiens, D. Marie, D. Marko, E. Niederberger, W. Tang, G. Eisenbrand, L. Meijer Nature Cell Biology 1999, Vol. 1, No. 1, 66-67 |
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| Preclinical activity of 17ß-[N-[N‘-(2-chloroethyl)-N‘-nitrosocarbamoyl]-L-alanyl]-5alpha-dihydrotestosterone
(E91) against tumour colony forming units and haematopotetic progenitor
cells P. Rank, R. Peter, H. Depenbrock, G. Eisenbrand, P. Schmid, H. Pitzl, A.R. Hanauske Europ. Journal of Cancer 1999, Vol.35, No.6, 1009-1013 |
| Probing the mechanism of the carcinogenic activation of N-nitrosodiethanolamine
with deuterium isotope effects: in vivo induction of DNA single strand
breaks and related in vitro assays R.N. Loeppky, A. Fuchs, C. Janzowski, C. Humberd, P. Gölzer, H. Scheider, G. Eisenbrand Chem. Res.Toxicol. 1998, 11, 1556-1566 |
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| Synthesis of 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidinopteridine
and novel derivatives free of positional isomers. Potent inhibitors
of cAMP-specific phosphodiesterase and of malignant tumor cell growth K.-H. Merz, D. Marko, T. Regiert, G. Reiss, W. Frank, G. Eisenbrand J. Med. Chem. 1998, 41 (24), 4733-4743 |
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| Novel steroid-linked conjugates of 17ß-[N-[N‘-(2-chloroethyl)-N‘-nitroso]
carbamoyl]amino acids and their antineoplastic activity against Noble
Nb prostate carcinoma model in rats W. Tang, M.R. Schneider, G. Eisenbrand Anti-Cancer Drug Design 1998, 13, 815-824 |
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| Induction of apoptosis by an inhibitor of cAMP-specific PDE in malignant
murine carcinoma cells overexpressing PDE activity in comparison to
their non malignant counterparts D. Marko, K Romanakis, H. Zankl, G. Fürstenberger, B. Steinbauer, G. Eisenbrand Cell Biochemistry and Biophysics 1998, 28, 75-101 |
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| 239 | Mutagene und kanzerogene Inhaltsstoffe offizineller chinesischer
Heilpflanzen G. Eisenbrand, W. Tang Zeitschrift für Phytotherapie 1998, 19, 39-42 |
| Potential nitrosamine formation and its prevention during biological
denitrification of red beet juice E. Kolb, M. Haug, C. Janzowski, A. Vetter, G. Eisenbrand Food Chem. Toxicol. 1997, 35, 219-224 |
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| Genotoxic effects of 2-trans-hexenal in human buccal mucosa
cells in vivo U. Dittberner, Beate Schmetzer, P. Gölzer, G. Eisenbrand, H. Zankl Mut. Res. 1997, 390, 161-165 |
| N-nitroso compounds in cosmetics, household commodities
and cutting fluids G. Eisenbrand, A. Fuchs. W. Köhl European Journal of Cancer Prevention 1996, 5 (supplement 1), 41-46 |
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| An approach towards more selective anticancer agents G. Eisenbrand, S. Lauck-Birkel, W.C. Tang Synthesis 1996, 10, 1246-1258 |
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| (E)-2-Hexenal-induced DNA damage and formation of cyclic 1,N2-(1,3-propano)-2'-deoxoguanosine
adducts in mammalian cells P. Gölzer, C. Janzowski, B.L. Pool-Zobel, G. Eisenbrand Chem. Res. Toxicol 1996, 9, 1207 - 1213 |
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| Untersuchungen zur Nitritbildung und zum Nitrosierungspotential
bei der heterotrophen biologischen Denitrifizierung von Trinkwasser
unter Laborbedingungen S. Kevekordes, M. Urban, W. Steffens, Ch. Janzowski, G. Eisenbrand, H. Dunkelberg Zbl. Hyg. 1996, 198, 462-472 |
| Synthesis of novel androgen-linked phosphoramide mustard prodrugs
and growth-inhibitory activity in human breast cancer cells T. Roth, W. Tang, G. Eisenbrand Anti-Cancer Drug Design 1995, 10, 655-666 |
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| Genotoxic effects of the alpha, beta-unsaturated aldehydes 2-trans-butenal,
2-trans-hexenal and 2-trans-, 6-cis-nonadienal U. Dittberner, G. Eisenbrand, H. Zankl Mutation Research 1995, 335, 259-265 |
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| Stable expression of human cytochrome P450 2E1 in V29 chinese hamster
cells W.A. Schmalix, M. Barrenscheen, R. Landsiedel, C. Janzowski, G. Eisenbrand, F. Gonzalez, E. Eliasson, M. Ingelmann-Sundberg, M. Perchermeier, H. Greim, J. Doehmer Eur. J. Pharmacol. Environ. Toxicol. Pharmacol. Section 1995, 293, 123-131 |
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| The influence of glutathione and detoxifying enzymes on DNA damage
induced by 2-alkenals in primary rat hepatocytes and human lymphoblastoid
cells G . Eisenbrand, J. Schumacher, P. Gölzer Chem. Res. Toxicol. 1995, 8, 40-46 |
