Research Group Manolikakes

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from the Manolikakes Lab


Open Positions

Undergraduate Students

Undergarduate students who are interested in organic chemistry, method development and the synthesis of biologically active molecules, should contact Georg Manolikakes (mail) or visit our labs (Geb. 54; 452-457). Topics for Bachelor theses, F-Praktika and Master-Theses with the oppurtunity to participate in interdisciplinary projects and the option of publication in peer-reviewed journals are available at any time.

We are currently looking for several students interested in conducting a master thesis in synthetic organic chemistry. A strong background in synthetic chemistry is required.

 

Graduate Students and Postdocs

We are always looking for highly motivated and qualified coworkers with strong passion for organic synthesis. If you are interested. please contact Georg Manolikakes by Email with all relevant documents (CV, list of publications and research summary). Please arrange to have at least two letters of recommendation.


News

Follow us on twitter: @ManolikakesLab

2024

January: New publication in Org. Lett. Big step for our group towards FAIR publishing. All primary data and physical reference substances available via Chemotion.

January: Two new preprints on ChemRxiv. Congratulations to Oluwaseun and Miro!

2023

November: Back to the roots - Georg will visit the Universities in Athens and Thessalonik and attend the Aristotle Conference on Chemistry.

September: Georg will present the group's newest results during a lecture tour in China- Many thanks to Zhi-Bing Dong (WIT) for hosting.

July:  Our collaborative work with Thorsten and Jessica from the Paul-Ehrlich-Institute on nitrated fatty acids as novel type of proteasome inhibitors has been published in Cell Chemical Biology.

April:  Georg recieved a Momentum grant from the VW-Foundation! The group will expand its investigations into a new field, the biochemical fixation of sulfur dioxide.

April:  Basti sucessfully defended his PhD thesis. Congratulations Dr. Jakob!

February: Our joint work with Marcel Deponte (RPTU) and Bruce Morgan (UdS) on the role of substrate promiscuity and hpyperoxidation susceptibility in the co-evolution of Prx5-type and Prx6-type 1-Cys peroxiredoxin mechanisms is now in ACS Catalysis.

January:  Our joint work with Christop Kerzig and Katja Heinze, both from JGU Mainz, using earth-abuandan Chromium-catalysts for a visible-light induced fixation of SO2 into organic molecules been published in ChemCatChem.

January:  Sara sucessfully defended her PhD thesis. Congratulations Dr. Krieg!

January:  Thais from the Faculdade de Ciências Farmacêuticas de Ribeirão Preto in Brasil joined as for a one year PhD-exchange funded by CAPES. Welcome Thais!

 

2022

December:  A good end for 2022. Miro's work on the stereoselective synthesis of fused nitrogen heterocycles with three contiguous sterocenters appeared online on Decmeber 31st in Eur. J. Org. Chem.

October:  The Carl-Zeiss Foundation will support Halocycles, a new joint research project with the JGU Mainz, in its CZS Breaktrough program with 4 Million Euros. In the next six years, we will develop new electrochemical techniques to recover halogens from waste products, leading to a circulat economy for halogenated organic compounds.

September:  Christina joined the group for here master thesis. Welcome and Good luck!

August:  Sara's 2nd geration route for the stereoselective synthesis of 2-oxyenamides has been published in Eur. J. Org. Chem. Congratulations and many thanks to Martin Breust for this fruitful collaboration.

August:  Nils joined the group for his master thesis. Welcome and Good luck!

August:  Kamil sucessfully defended his PhD theses. Congratulations Dr. Hofman!

July:  ETOS (Electrifying Technical Organic Syntheses) has been selected as one of the seven new BMBF Clusters4Future. In the next three years, we will look intoi new process for electrochemical sulfur dioxide fixation. Congratulations to everybody involved, in particular the two coordinators Ulrike Krewer and Sigi Waldvogel.

May:  Today, Georg recieved the State Teaching Award (Landeslehrpreis Rheinland-Pfalz 2022) from Science Minister Clemens Hoch.

March:  Andi sucessfully defended his PhD theses. Congratulations Dr. Diehl!

March:  Marius's new npovel method for the direct C-H-sulfonyation of N-heterocycles has been published in Tetrahedron Chem.

January:  Amelie joined the group for her master thesis. Welcome and Good luck!

2021

November:  Our long-term NFA-collaboration on nitro fatty acids resulted in a new publication on the target-specific-structure-activity relationship of anti-inflammatory nitro fatty acids. Congratulations to all coauthors!

September:  Two more publications accpeted in ChemSusChem and Eur. J. Org. Chem. Congratulations to all coauthors!

August:  Just back from vaccation and two publications accpeted in Future Med. Chem. and Angew. Chem. Good start! Congratulations to all coauthors!

July:  Mohamed and Cedrics spotlight on nitroolefin synthesis via direct nitration of alkenes has been published in SynOpen!

July:  Our joint review with the Waldvogel group on photo- and electrochemical fixation of sulfur dioxide has been published in Chem. Commun.!

May:  Julian recived a PhD scholarship from the Evangelisches Studienwerk. Congratulations!

April:  Mohamed's streamlined NFA synthesis has been published in Eur. J. Org. Chem. It already attracted some attention from Chemistry Views. Congratulations!

February:  Saad's work on organoselenium compounds as novel chemisensitizers has been published in Bioorg. Chem. Congratulations!

February:  Julian (re)joined the group for his PhD. Welcome back!

January:  Miro joined the group for his master thesis. Welcome and Good luck!

2020

September:  Check out the emerging potential of Michael-acceptor containing drugs in our latest Front. Pharmacol. review with contributors from literally all over the world.

August:  Philipp sucesfully defended his PhD thesis. Congratulations Dr. Kramer!

April:  A greener version of the Petasis reaction? Andi's work on the 3-component synthesis of arylglycines using carboxylic acids as nucleophiles has been published in ChemCatChem.

April:  Our joint review with Shuial Liang from Qingdao University on the synthesis and application of sulfinate salts has been published in EJOC.

January:  Phlilipp's and Miro's work on the iron-mediated oxysulfonylation of enamides has been published in J. Org. Chem. Congratulations.

2019

October:  Ichraf started her 5-month PhD-exchange project. Welcome and Good luck!

October:  Cedric joined the group for his PhD wih a DAAD scholarship. Welcome and Good luck!

September:  Prof. Gomaa's work in our lab has resulted in a first publication in Synth. Commun. Congratulations!

July:  Five in one go. Jenny's and Philipp's new domino reaction for the stereoselective synthesis of tetrahydropyrans with five continuous stereogenic centers has been accepted for publication in Angewandte Chemie. Congratulations!

May:  Sara's and Philipp's work on the Mn(OAc)3-mediated direct C-H-sulfonylation of enmaides has been published in Org. Biomol. Chem. Congratulations!

May:  Sara and Basti joined the group for their PhD theses. Welcome and Good luck!

April:  What an honor! During the 5th International Conference on Synthesis and Complexing in Moscow Georg recieved a prestiguous RUDN University Honorary Fisherman Award.

April:  Alexandre joined the group for his master thesis. Welcome and Good luck.

March:  Alexander's work on the structural elucidation of a PDI-photoredox-catalyst has been published in CrystEngComm. Congratulations to everbody involved.

March:  Mohamed started his 2-year PhD exchange project. Welcome and Good luck!

January:  Jule and Nai sucessfully defended their PhD theses. Congratulations Dr. Halli and Dr. Liu!

2018

October:  Three in One (Pot)! Our latest paper on the diastereoselective One-pot-synthesis of 1,3-diamines with three continuous stereocenters has been published in The Journal of Organic Chemistry. Congratulations to Jule, Philipp and Jenny.

October:  Sara started her Master Thesis. Welcome!

September:  Our collaboration with Zhejiang Sci-tech University on the visible-light mediated sulfur dioxide fixation resulted in a second publication. Congratulations to Nai-wei, Andre, Zhenkai and Hongjun for their publication in European Journal of Organic Chemistry.

September:  Ise sucessfully finished her Master Thesis. Congratulations and all the best for your PhD!

August:  Conference season! Georg will present the group's latest reults at the 7th EuCheMS Chemistry Congress in Liverpool and the MCR 2018 in Düsseldorf.

August:  Kamil's and Nai-Wei's Minireview on the combination of radicals and sulfur dioxide has been published in the Chemistry - A European Journal special issue 7th EuCheMS Chemistry Congress, Liverpool. Congratulations to this Review Showcase.

August:  Prof. Gomaa from Minia University, Egypt is joing our lab for three months. Welcome!

July:  Congratulations to Andreas, Omar and Eleni on their latest work using sulfonamides a building blocks in the Petasis reaction, which has been publisehd online in Synthesis.

June:  Our most recent work on the visible-light mediated fixation of sulfur dioxide has been accepted for publication in Green Chemistry. Congratulations to Nai-Wei and to Zhengkai Chen and Hongjun Ren, our partners from Zhejiang Sci-tech University.

June:  A new cure for cancer? Our joint project with Jessica Roos and Thorsten J. Maier (University-Hospital Frankfurt) on suppresion of tumor-growth by nitro-fatty acids has been published in Biochemical Pharmacology. Congratulaitions to everybody invloved in this truly multi-disciplinary effort.

May:  Saad's work on cyctoprotective and antioxidant properties of organic selenides has been published in Bioorganic Chemistry. Congratulations to everybody involved.

May:  Shuai sucessfully defended his PhD thesis. Congratulations Dr. Liang!

March:  A warm welcome to Ise, who joined the goup for her Master thesis!

January:  A productive start into 2018!Two manuscripts accepted for publication in Organic Letters.Congratulations to Nai-Wei, Kamil and Andre for their work on dual Nickel/photoredox catalyzed sulfone synthesis and to Philipp and Julia for their stereoselective one-pot construction of novel fused pyrimidoisoindoles.

January:  First Days at TU Kaiserslautern. The Manolikakes group moved to their new home!

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